Group Leader
© IMB Mainz
Prof. Dr. Lukas Stelzl
Positions held
Since 2024: Professor of Biomolecular Simulations, Johannes Gutenberg University Mainz and Adjunct Director, Institute of Molecular Biology (IMB), Mainz
2020 – 2024: ReALity Junior Group Leader and IMB Associate Group Leader, Faculty of Biology and KOMET1, Institute of Physics, Johannes Gutenberg University Mainz and Institute of Molecular Biology (IMB), Mainz
2015 – 2020: Postdoctoral fellow, Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main
Education
2015: DPhil in Biochemistry, University of Oxford, UK
2010: MBiochem, Molecular and Cellular Biochemistry, University of Oxford, UK
Postdocs
| Research interest | Code | Contact | |
|---|---|---|---|
 Xiaofei Ping | xiaoping@students.uni-mainz.de Johannes-von-Müller-Weg 6 Nat.- and Med.-building: 1321 55128 Mainz Room 00-125 |
PhD Students
| Research interest | Code | Contact | |
|---|---|---|---|
 Ritika Aggarwal | I am interested in studying the how IDR regions of E3 ligase enzymes attract the target substrates. My particular interest is in HUWE1 ligase, being promiscuous in nature, I want to understand what is the mechanism of actions of binding to multiple substrates using all atomistic, coarse grain simulations and machine learning approaches. | aggarwar@uni-mainz.de Johannes-von-Müller-Weg 6 Nat.- and Med.-building: 1321 55128 Mainz Room 00-125 | |
 Lucia Baltz | I use molecular dynamics simulations and machine learning-based contact analysis to study interaction patterns and dynamics during condensate formation. | GitHub SFB1551 | lubaltz@uni-mainz.de Johannes-von-Müller-Weg 6 Nat.- and Med.-building: 1321 55128 Mainz Room 00-123 |
| Denis Arribas Blanco | darribas@uni-mainz.de Johannes-von-Müller-Weg 6 Nat.- and Med.-building: 1321 55128 Mainz | ||
 Jonas Paulus | My research interest focuses on protein - ligand binding free energy, currently i am focusing on protein conformational changes and their impact in ligand binding. | GitHub | jpaulu01@uni-mainz.de Johannes-von-Müller-Weg 6 Nat.- and Med.-building: 1321 55128 Mainz Room 00-125 |
 Leon Persch | I use molecular dynamics and alchemical free energy perturbation (FEP) calculations to predict how mutations and ligand modifications affect binding free energies at atomic resolution. | LinkedIn | lepersch@students.uni-mainz.de lpersch@uni-mainz.de Johannes-von-Müller-Weg 6 Nat.- and Med.-building: 1321 55128 Mainz Room 00-125 |
| Cyrille Ngueldjou Tahabo | cngueldj@uni-mainz.de Johannes-von-Müller-Weg 6 Nat.- and Med.-building: 1321 55128 Mainz Room 00-122 | ||
| Vasilis Xenidis | xenidisv@uni-mainz.de Johannes-von-Müller-Weg 6 Nat.- and Med.-building: 1321 55128 Mainz Room 00-123 | ||
| Mahesh Yadav | GitHub | mahesh.yadav@uni-mainz.de Staudingerweg 9 Phys.- and Mat.-building: 2413 55128 Mainz Room 01-517 | |
| Emanuele Zippo | zippoema@uni-mainz.de Johannes-von-Müller-Weg 6 Nat.- and Med.-building: 1321 55128 Mainz Room 00-123 |
Master Students
| Name | Master thesis |
|---|---|
| Olga Corrado | Exploring the Effect of Post-Translational Modifications on TDP-43 Phase Separation |
| Christian Fabri | Extending Neural Network-Based Backmapping for Post-Translationally Modified Protein Condensates |
| Stefan Grünewald Borras | |
| Theresa Huntemann | Hierachcial contact analysis of biomolecules condensates based on interface dynamics. |
| Sergios Leftheriotis | |
| Antonia Preuß | |
| Moxian Qian | Stochastic Path Sampling for Protein Conformational Ensembles |
| Minoo Rostami | Antimicrobial peptides interacting with bacterial membranes |
| Sascha Schwarzhaupt | |
| Joshua Zeitvogel |
Bachelor Students
| Name | Bachelor thesis |
|---|---|
| Beyza Bulut | |
| Dennis Martin | Molecular Dynamics Studies on the Mechanism of Action of Fludioxonil in the MoHik1p Signal Transduction System of Magnaporthe oryzae |
| Jim Roth | Intramolecular Contacts and Conserved-Region Helicity in TDP-43 |
Student Research Assistants
| Name |
|---|
| Philip Frederic Mundt |
| Rebecca Ziora |
Alumni
| Name | Research interest | Contact |
|---|---|---|
| Kumar Gaurav | kugaurav@uni-mainz.de | |
| Arya Changiarath Sivadasan |